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ea0078OC9.5 | Oral Communications 9 | BSPED2021

Variability of advice and education for steroid sick day dosing in Duchenne Muscular Dystrophy: Results of a UK patient survey

Thakrar S , Cheung MS , Johnson A , Katugampola H , Manzur A , Muntoni F , Mushtaq T , Turner C , Wood C , Guglieri M , Wong SC

Introduction: The use of long-term oral corticosteroids in DMD leads to secondary adrenal insufficiency. The 2018 international care consensus recognizes this important issue and recommends emergency plans to be in place. Aim: This online UK-wide patient survey aims to determine the advice/education given for emergency stress dose plans and the impact of the COVID-19 pandemic in corticosteroid-treated young people with DMD. Methods...

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ea0003p269 | Steroids | BES2002

Size at birth, gestational age and cortisol secretion in adult life: Do multiple mechanisms underlie fetal programming of the hypothalamic-pituitary-adrenal axis?

Kajantie E , Phillips D , Dunkel L , Andersson S , Barker D , Forsen T , Osmond C , Wood P , Tuominen J , Eriksson J

Objective. Recent studies suggest that in utero programming of the hypothalamo-pituitary-adrenal axis is important in explaining the link between small size at birth and adult cardiovascular disease. We therefore examined the relationship between adult cortisol concentration and measurements at birth.Subjects. 420 men and women (mean age 69.5, range 65.0-75.8 yrs) born and living in Helsinki, Finland, with detailed birth records.<p class="ab...

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Endocrine Abstracts

Variability of advice and education for steroid sick day dosing in Duchenne Muscular Dystrophy: Results of a UK patient survey

Size at birth, gestational age and cortisol secretion in adult life: Do multiple mechanisms underlie fetal programming of the hypothalamic-pituitary-adrenal axis?

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